Harry Wilson is a major doubt for the start of Wales’ Nations League campaign as they return to League A.

The Leeds United forward had been named in Craig Bellamy’s squad to face Portugal, Denmark and Norway in September and October.

But Wilson’s club boss Daniel Farke confirmed on Friday the 29-year-old has suffered a muscle injury to his quadriceps that will rule him out of Sunday’s Premier League game at home to Crystal Palace.

“Harry Wilson is out of this game, a quad injury, he reported some problems after the last game and also during this training week,” Farke said of the 69-cap player who has scored 17 times for his country.

“He will also probably miss the Welsh games, so definitely not good news for him and also not for the Welsh team.”

While Wales may want to do their own assessment, the news is already a major blow for Bellamy given Wilson’s outstanding international form over the past 12 months.

Bellamy is already without key defender Joe Rodon, Wilson’s team-mate at Elland Road, as well as Cardiff City defensive pair Dylan Lawlor and Ronan Kpakio.

Two more Cardiff players, forwards Isaak Davies and Rubin Colwill are also unavailable for selection because of injury, along with Wrexham attacker Nathan Broadhead.

Wales travel to face Portugal on 24 September in the first of four fixtures in this newly extended international break, with a home match against World Cup quarter-finalists Norway sandwiched by two games with Denmark.

Wales – 38th in the world rankings, their lowest position since August 2014 – then travel to Copenhagen to take on a Denmark side ranked 21st in the world.

Norway, who were World Cup quarter-finalists, then visit Cardiff on 1 October before the return home game against Denmark on 4 October.